miasis

Ocimum gratissimum


(In territories with significant traditional TRAMIL use)

  • Dominican Republic : albahaca vaca
  • Guatemala : basen
  • Haiti : atiyayo
  • Haiti : gwo fonbazen
  • Saint Lucia : vanne van

Significant uses found by the TRAMIL surveys

  fresh leaf, crushed, applied in nose4

Recommandations
Preparation and posology
References

According to published and other information:

Use for abdominal pain and flatulence, asthenia and weakness is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, and on available published scientific information.

Should there be a notable worsening of the patient’s condition, or should abdominal pain last more than 3 days, seek medical attention.

Use for torsalo (myiasis) is classified as REC, based on the significant traditional use (OMS/WHO)4 documented in the TRAMIL surveys.

For topical application, strict hygiene measures should be observed in order to avoid contamination or additional infection.

Not for use during pregnancy, during lactation or by children under 5 years old.

The leaves of Ocimum gratissimum are widely used for human consumption.

For abdominal pain and flatulence:

Prepare a decoction or infusion with 5-7 grams (1-2 spoonfuls) of leaves in 1/2 liter (2 cups) of water.  In case of decoction, boil for at least 10 minutes in a covered pot (possibly, with a pinch of salt).  For infusion, add boiling water to the leaves, cover and leave to cool.  Filter and drink 1 cup 3 times per day.

For abdominal pain, there is no available information establishing a means of preparation and dosage regarding the leaf juice other than that referred to by traditional use.

For torsalo (myiasis):

There is no available information establishing a means of preparation and dosage other than that referred to by traditional use.

Any medicinal preparation must be preserved cold and used within the 24 hours.

1 WENIGER B, 1987-88 Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

2 WENIGER B, ROUZIER M, 1986 Enquête TRAMIL. Service Oecuménique d'Entraide SOE, Port au Prince, Haïti.

3 JEAN-PIERRE L, 1988 TRAMIL survey. St. Lucia national herbarium, Castries, St Lucia.

4 GIRON L, 1988 Encuesta TRAMIL (Costa atlántica). Centro Mesoamericano de Tecnología CEMAT, Guatemala, Guatemala.

5 WHO, 1991 Guidelines for the assessment of herbal medicines. WHO/TRM/91.4. Programme on Traditional Medicines, WHO, Geneva, Switzerland.

6 WENIGER B, SAVARY H, DAGUIHL R, 1984 Tri phytochimique de plantes de la liste TRAMIL. Laboratoire de chimie des substances naturelles, Faculté de Médecine et de Pharmacie, Université d'Etat d'Haïti, Port au Prince, Haïti.

7 ZAMUREENKO VA, TOKAREVA VY, KLYUEV NA, KARPOVA TI, GRANDBERG TI, 1981 Identification of sesquiterpene hydrocarbons of essential oil from Ocimum gratissimum L. Izv Timiryazevsk S-Kh Akad 1981(4):153-155.

8 NTEZURUBANZA L, SCHEFFER JJC, BAERHEIM-SVENDSEN A, 1987 Composition of the essential oil of Ocimum gratissimum grown in Rwanda. Planta Med 53(5):421-423.

9 ARCTANDER S, 1960 Perfume and flavor materials of natural origin. Elizabeth, USA: Stephen Arctander.

10 HEGNAUER R, 1973 Chemotaxonomy der Pflanzen. Basel, Schweiz: Birkhauser Verlag. 6:882.

11 MAIA JGS, RAMOS LS, LUZ AIR, DA SILVA ML, ZOGHBI MG, 1988 Uncommon Brazilian essential oils of the Labiatae and Compositae. In: Flavors and fragrance: a world perspective, Proceedings of the 10th International Congress of Essential Oils. Lawrence BM, Mookherjee BD, Willis BJ, Eds. New York, USA: Elsevier Sci Publ. p177-188.

12 JANSSEN AM, SCHEFFER JJC, NTEZURUBANZA L, SVENDSEN AB, 1989 Antimicrobial activities of someOcimum species grown in Rwanda. J Ethnopharmacol 26(1):57-63.

13 NIGAM M, KHOSLA MK, BRADU BL, TANDON N, 1988 Hydration of terpene fraction of "Clocimum" oil and isolation of pure myrcene. Parfume Kosmet 69(5):285-286.

14 AWUAH RT, 1989 Fungitoxic effects of extracts from some West African plants. Ann Appl Biol 115(3):451-453.

15 OFFIAH VN, CHIKWENDU UA, 1999 Antidiarrhoeal effects of Ocimum gratissimum leaf extract in experimental animals. J. Ethnopharmacol 68(1-3):327-330.

16 AZIBA PI, BASS D, ELEGBE Y, 1999 Pharmacological investigation of Ocimum gratissimum in rodents. Phytother Res 13(5):427-429.

17 NJOKU CJ, ASUZU IU, 1998 The anthelmintic effects of the leaf extract of Ocimum gratissimum (L.). Phytomedicine 5(6):485-488.

18 ADESINA SK, 1982 Studies on some plants used as anticonvulsants in Amerindian and African traditional medicine. Fitoterapia 53:147-162.

19 EL KELTAWI N, MEGALLA S, ROSS S, 1980 Antimicrobial activity of some Egyptian aromatic plants. Herbal Pol 26(4):245-250.

20 MADEIRA SVF, MATOS FJ, LEAL-CARDOSO JH, CRIDDLE DN, 2002 Relaxant effects of the essential oil of Ocimum gratissimum on isolated ileum of the guinea pig. J Ethnopharmacol 81(1):1-4.

21BUDAVARI S (Ed.), 2001 The Merck index: an encyclopedia of chemical, drugs, and biologicals. 30th ed. White House Station, New Jersey, USA: Merck & Co., Inc. p1676.

22 ONAJOBI FD, 1986 Smooth muscle contracting lipid-soluble principles in chromatographic actions of Ocimum gratissimum. J Ethnopharmacol 18(1):3-11.

23 LOGARTO PARRA A, TILLAN CAPO J, VEGA MONTALVO R, GONZALEZ YC, 1999 Toxicidad aguda oral de extractos hidroalcohólicos de plantas medicinales. Rev Cubana Planta Med 4(1):26-28.

24 DHAWAN BN, PATNAIK GK, RASTOGI RP, SINGH KK, TANDON JS, 1977 Screening of Indian plants for biological activity. VI. Indian J Exp Biol 15(3):208-219.

25 LOGARTO PARRA A, SILVA YHEBRA R, GUERRA SARDINAS I, IGLESIAS BUELA L, 2001 Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts. Phytomedicine 8(5):395-400.

26 GUERRA MJ, LOPEZ M, BOUCOURT E, FUENTES V, MORON F, 2002 Toxicidad aguda (DL50) de decocción de hojas frescas de Ocimum gratissimum L.Informe TRAMIL. Laboratorio Central de Farmacología. Facultad de Medicina Dr. Salvador Allende. Ciudad de La Habana, Cuba.

27 GUERRA MJ, LOPEZ M, BOUCOURT E, FUENTES V, MORON F, 2002 Clases toxicas agudas de decocción (30%) de hojas frescas de Ocimum gratissimum L.Informe TRAMIL. Laboratorio Central de Farmacología. Facultad de Medicina Dr. Salvador Allende. Ciudad de La Habana, Cuba.

28 GUERRA MJ, LOPEZ M, BOUCOURT E, FUENTES V, 2002 Toxicidad aguda (DL50) de extracto fluido 30% de hojas secas de Ocimum gratissimum L.Informe TRAMIL. Laboratorio Central de Farmacología. Facultad de Medicina Dr. Salvador Allende. Ciudad de La Habana, Cuba.

29 GUERRA MJ, LOPEZ M, BOUCOURT E, FUENTES V, 2002 Genotoxicidad in vivo: ensayo de micronúcleos en médula ósea de extracto fluido 30% de hojas secas de Ocimum gratisimum L.Informe TRAMIL. Laboratorio Central de Farmacología. Facultad de Medicina Dr. Salvador Allende, Ciudad de La Habana, Cuba.