amenorrhoea

(In territories with significant traditional TRAMIL use)

Haiti:

  • bètrouj

Dominican Republic:

  • remolacha
Significant uses found by the TRAMIL surveys

root, juice, taken orally1

Recommendations Preparation and Dosage References

According to published and other information:

Use for period delay (amenorrhoea), asthenia and weakness is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, and on available published scientific information.

Due to health risks involved with asthenia and weakness, an initial medical evaluation is recommended.  The use of this resource can be considered complementary to medical treatment, unless it is contraindicated.

The root of Beta vulgaris is widely used for human consumption and is an industrial source of sucrose.

For period delay (amenorrhoea), asthenia and weakness:

Wash the fresh crude root. Prepare 100 mL juice. Drink one or more times a day29.

1 WENIGER B, ROUZIER M, 1986
Enquête TRAMIL. Service Oecuménique d’Entraide SOE, Port au Prince, Haïti.

2 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

3 WENIGER B, 1987-88
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

4 CHIERICI L, 1953
Allantoin and tyrosine in beets. Ateneo Parmense 24:185-188.

5 DUBBELS R, REITER RJ, KLENKE E, GOEBEL A, SCHNAKENBERG E, EHLERS C, SCHIWARA HW, SCHLOOT W, 1995
Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography-mass spectrometry. J Pineal Res 18(1):28-31.

6 TYIHAK E, 1964
Effective component in the effect of the red beet (Beta vulgaris var conditiva) on tumors. Naturwissenschaften 51:315-316.

7 IKEKITA M, MORIYA H, MORIWAKI C, RURIKAWA T, 1979
Some properties of anti-bradykinin substance from beet (Beta vulgaris L. var rapa Dumort. f rubra DC.) roots. Yakugaku Zasshi 99:607-611.

8 NEURATH GB, DUNGER M, PEIN FG, AMBROSIUS D, SCHREIBER O, 1977
Primary and secondary amines in the human environment. Food Cosmet Toxicol 15(4):275-282.

9 PARFENENKO VV, BUZINA GV, LUTSENKO OK, 1974
Production of gel-forming beet pectin in the presence of 1.1% hydrochloric acid. Khlebopek Konditer Prom 1974(10):20.

10 CHOLLET MM, 1950
Sucrose and raffinose in beets. Bull Soc Bot Fr 1950:173-177.

11 PIATTELLI M, MINALE L, PROTA G, 1965
Pigments of centrospermae. III. Betaxanthins from Beta vulgaris L. Phytochemistry 4:121-125.

12 GEORGIEV VG, WEBER J, KNESCHKE EM, DENEV PN, BLEY T, PAVLOV AI, 2010
Antioxidant activity and phenolic content of betalain extracts from intact plants and hairy root cultures of the red beetroot Beta vulgaris cv. Detroit dark red. Plant Foods Hum Nutr 65(2):105-111.

13 HERRMANN K, 1957
Oxidative enzymes and phenolic substrate in vegetables and fruit. I. Hydroxycinnamic acids. Z Lebensm-Unters Forsch 106:341-348.

14 BURBA M, NITZSCHKE U, 1974
Oxalic acid in sugar beet roots. Int Sugar J 76:326.

15 TAKAHASHI H, SASAKI T, ITO M, 1987
New flavonoids isolated from infected sugar beet roots. Bull Chem Soc Japan 60(6):2261-2262.

16 ELLIGER CA, HALLOIN JM, 1994
Phenolics induced in Beta vulgaris by Rhizoctonia solani infection. Phytochemistry 37(3):691-693.

17 YOSHIKAWA M, MURAKAMI T, KADOYA M, MATSUDA H, MURAOKA O, YAMAHARA J, MURAKAMI N, 1996
Medicinal foodstuffs. III. Sugar beet. (1): Hypoglycemic oleanolic acid oligoglycosides, betavulgarosides I, II, III, and IV, from the root of Beta vulgaris L. (Chenopodiaceae). Chem Pharm Bull 44(6):1212-1217.

18 YOSHIKAWA M, MURAKAWI T, KADOYA M, YAMAHARA J, MATSUDA H, 1998
Medicinal foodstuffs. XV. Sugar beet. (2): Structures of betavulgarosides V, VI, VII, VIII, IX, and X from the roots and leaves of sugar beet (Beta vulgaris L., Chenopodiaceae). Chem Pharm Bull 46(11):1758-1763.

19 KUJALA TS, LOPONEN JM, KLIKA KD, PIHLAJA K, 2000
Phenolics and betacyanins in red beetroot (Beta vulgaris) root: distribution and effect of cold storage on the content of total phenolics and three individual compounds. J Agric Food Chem 48(11):5338-5342.

20 DUKE JA, ATCHLEY AA, 1986
Handbook of proximate analysis tables of higher plants. Boca Raton, USA: CRC Press, p26.

21 MORON F, 1990
Actividades biológicas de Beta vulgaris. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Medicina “Dr. Salvador Allende”, Instituto Superior de Ciencias Médicas de La Habana, La Habana, Cuba.

22 CARBALLO A, RODRIGUEZ A, RODRIGUEZ O, LLENDERROZOS A, 1992
Efectividad de la administración del zumo de raíces de remolacha (Beta vulgaris L.) en el control de la astenia. Estudio clínico controlado. Informe TRAMIL. Instituto Superior de Ciencias Médicas. Santa Clara, Cuba.

23 PRAHOVEANU E, ESANU V, ANTON G, FRUNZULIC S, 1986
Prophylactic effect of a Beta vulgaris extract on experimental influenza infection in mice. Rev Roum Med Virol 37(2):121-124.

24 JOSEPH H, GRANDGUILLOTTE M, 1986
Recherches bibliographiques. SNPG, Guadeloupe. TRAMIL II, Santo Domingo, República Dominicana, UASD/enda-caribe.

25 RAO VSN, DASARADHAN P, KRISHNALAH KS, 1979
Antifertility effect of some indigenous plants. Indian J Med Res 70:517-520.

26 NAVRATIL B, ZEMAN L, 1976
Effect of the daily ration and the type of complete mixed feed fed to pregnant sows on the number and weight of piglets. Zivocisna Uyrpba 21:295-303.

27 ELBE JH, SCHWARTZ SJ, 1981
Absence of mutagenic activity and an short-term toxicity study of beet pigments as food colorants. Arch Toxicol 49:93-98.

28 VAN DER WALT SJ, STEYN DG, 1946
Recent investigations into the toxicity of plants, etc.XV. Onderstepoort J Vet Sci Animal Ind 21(1):45-55.

29 GREER MA, ASTWOOD EB, 1948
The antithyroid effect of certain foods in man as determined with radioactive iodine. Endocrinology 43:105-119.

30 VANACLOCHA B, CAÑIGUERAL S, (eds.) 2003
Beta vulgaris. En: Fitoterapia. Vademecum de Prescripción. 4ta Edición. Editorial MASSON, Barcelona, España, p428.

(In territories with significant traditional TRAMIL use)

Haiti:

  • bwa dchèn
  • bwadoèn

Dominican Republic:

  • roble
Significant uses found by the TRAMIL surveys

  bark, decoction with salt, orally1

Recommendations Preparation and Dosage References

According to published and other information:

Use for stomach pain and delayed menstruation (amenorrhea) is classified as REC, based on the significant traditional practice documented in the TRAMIL surveys, toxicity studies, validation and published scientific information available.

Should there be a notable worsening of the patient’s condition, or should stomach pain last more than 3 days, medical attention should be sought for.

The use for fever is also classified as REC, based on the significant traditional use documented in the TRAMIL surveys, toxicity studies and published scientific information available.

Should there be a notable worsening of the patient’s condition, or should fever last more than 2 days, medical attention should be sought for.

Not for use by women during pregnancy as it may lead to abortion, during lactation, or by children under 3 years old.

Not for use for more than seven consecutive days in any class of patient.

For period delay (amenorrhea) and stomach pain:

Prepare a decoction with 20 grams of bark pieces in 1 liter (4 cups) of water, with or without a pinch of salt, depending on use, boil for a minimum of 10 minutes in a covered pot.  Sift, leave to cool down, and drink 1 cup every 6 hours14.

For fever:

Prepare a decoction with 10 grams of fresh leaves in 1 liter (4 cups) of water with a pinch of salt; boil for at least 10 minutes in a covered pot. Strain, leave to cool down, and drink 1 cup every 6 hours14.

1 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

2 CHAUHAN AK, DOBHAL MP, UNIYAL PN, 1988
Phytochemical investigation of Catalpa longissima L. Part I. Herba Pol 34(1/2):3-5.

3 DUKE J, 1999
Chemicals and their biological activities in: Catalpa longissima (Jacq.) Dum.Cours. Dr. Duke’s Phytochemical and Ethnobotanical Databases. USDA-ARS-NGRL, Beltsville Agricultural Research Center, Beltsville, USA, Nov.20,2000. URL: www.ars-grin.gov/duke/

4 HERRERA J, 1988
Determinación de actividades biológicas de vegetales utilizados en medicina tradicional. Trabajo TRAMIL. Dep. de Farmacología, Facultad de Salud, Universidad del Valle, Cali, Colombia.

5 SOUZA BRITO A, 1995
Actividad farmacológica de Catalpa longissima. Trabajo TRAMIL. Dep. de Fisiología y Biofísica, Universidad de Campinas, Campinas, Brasil.

6 NEGWER M, 1987
Organic-chemical drugs and their synonyms (an international survey), 6th ed. Berlin, Germany: Akademie-Verlag.

7 SOUZA BRITO A, 1995
Toxicidad aguda de Catalpa longissima. Trabajo TRAMIL. Dep. de Fisiología y Biofísica, Universidad de Campinas, Campinas, Brasil.

(In territories with significant traditional TRAMIL use)

Guatemala:

  • aguacate

Dominican Republic:

  • aguacate

Mexico:

  • aguacate

Barbados:

  • pear tree

Martinique:

  • zaboka
Significant uses found by the TRAMIL surveys

(and/or abortifacient) : leaf or fruit, decoction, orally1

Recommendations Preparation and Dosage References

According to published and other information:

Use for amenorrhea is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, toxicity studies, scientific validation and available published scientific information.

Use for asthma, bronchitis, flatulence, urinary infection and cough is classified as REC, based on the significant traditional use documented in the TRAMIL surveys and toxicity studies.

Should there be a notable worsening of the patient’s condition, or should asthma, bronchitis or cough last more than 5 days, or should urinary infection persist for more than 3 days, seek medical attention.

Due to the risks of documented interactions with warfarin and monoamine-oxidase inhibitors (MAOI), ingestion of the fruit decoction should be avoided by persons taking these medicines5.

Not for use during lactation or by children under 3 years old.

 

Not for use during pregnancy because it may have abortifacient effect.

The fruit of Persea americana is widely used for human consumption.

For amenorrhea, asthma, bronchitis, flatulence, urinary infection and cough:

Prepare a decoction with 20 grams (3 spoonfuls) of ground leaf in 1 liter (4 cups) of water, boil for at least 10 minutes in a covered pot.  Filter, allow to cool and drink 1/2-1 cup 3-4 times a day26.

Any medicinal preparation must be preserved cold and used within the 24 hours.

1 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

2 GIRON L, 1988
Encuesta TRAMIL (Costa atlántica). Centro Mesoamericano de Tecnología CEMAT, Guatemala, Guatemala.

3 FAUJOUR A, MURREY D, CHELTENHAM-CORBIN B, CARRINGTON S, 2003
TRAMIL survey. enda-caribbean, IICA & UAG, Saint Thomas, Barbados.

4 LONGUEFOSSE JL, NOSSIN E, 1990-95
Enquête TRAMIL. Association pour la valorisation des plantes médicinales de la Caraïbe AVPMC, Fort de France, Martinique.

5 MENDEZ M, MEDINA ML, DURAN R, 1996
Encuesta TRAMIL. Unidad de recursos naturales, Centro de Investigación Científica de Yucatán CICY, Mérida, México.

6 CANIGUERAL S, VILA R, RISCO E, PEREZ F, PORTILLO A, FREIXA B, MILO B, VANACLOCHA B, RIOS JL, MORALES MA, ALONSO JR, BACHILLER LI, PERIS JB, STUBING G, 2002
Persea americana. Vademecum de Fitoterapia, Editorial Masson, Barcelona, España, Feb. 26, 2003. URL: www.masson.es/book/fitoterapia.html

7 BERGH BO, SCORA RW, STOREY WB, 1973
Comparison of leaf terpenes in Persea subgenus persea. Bot Gaz (Chicago) 134(2)130-134.

8 KING JR, KNIGHT RJ, 1992
Volatile components of the leaves of various avocado cultivars. J Agric Food Chem 40(7):1182-1185.

9 DE ALMEIDA AP, MIRANDA MMFS, SIMONI IC, WIGG MD, LAGROTA MHC, COSTA SS, 1998
Flavonol monoglycosides isolated from the antiviral fractions of Persea americana (Lauraceae) leaf infusion. Phytother Res 12(8):562-567.

10 MERIÇLI F, MERIÇLI AH, YILMAZ F, YÜNCÜLER G, YÜNCÜLER O, 1992
Flavonoids of avocado (Persea americana) leaves. Acta Pharm Turc 34(2):61-63.

11 BATE-SMITH EC, 1975
Phytochemistry of proanthocyanidins. Phytochemistry 14(4):1107-1113.

12 MURAKOSHI S, ISOGAI A, CHANG CF, KAMIKADO T, SAKURAI A, TAMURA S, 1976
The effects of two components from avocado leaves (Persea americana) and related compounds on the growth of silkworm larvae, Bombyx mori. Nippon Oyo Dobutsu Konchu Gakkaishi 20:87-91.

13 CACERES A, GONZALEZ S, GIRON L, 1998
Demostración de la actividad antimicrobiana de plantas TRAMIL en base a los usos populares en la cuenca del Caribe. Informe TRAMIL. Laboratorio de productos fitofarmacéuticos Farmaya y Facultad de ciencias químicas y farmacia, Universidad de San Carlos, Guatemala, Guatemala.

14 HERRERA J, 1986
Determinación de actividades biológicas de vegetales utilizados en medicina tradicional. Informe TRAMIL. Dep. de Farmacología, Facultad de Salud, Universidad del Valle, Cali, Colombia.

15 GARCIA GM, COTO MT, GONZALEZ CS, PAZOS L, 1999
Actividad bronquial del extracto acuoso de hoja fresca de Persea americana. Informe TRAMIL. Laboratorio de Ensayos Biológicos LEBi, Escuela de Medicina, Universidad de Costa Rica, San Pedro, Costa Rica.

16 PAZOS L, COTO T, GONZALEZ S, QUIROS S, 2003
Tránsito intestinal, en ratones, del extracto acuoso de hojas frescas de Persea americana. Informe TRAMIL. Laboratorio de Ensayos Biológicos LEBi, Escuela de Medicina, Universidad de Costa Rica, San Pedro, Costa Rica.

17 MORON FJ, GARCIA AI, VICTORIA MC, MOREJON Z, LOPEZ M, BACALLAO Y, FUENTES V, 2008
Acción analgésica de la decocción de hojas frescas de Persea americana Mill. (aguacate) en ratones. Trabajo TRAMIL. Laboratorio Central de Farmacología, Facultad de Medicina “Dr. Salvador Allende”, La Habana, Cuba.

18 ADEYEMI OO, OKPO SO, OGUNTI OO, 2002
Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana Mill Lauraceae. Fitoterapia 73(5):375-380.

19 HERRERA J, 1988
Determinación de actividades biológicas de vegetales utilizados en medicina tradicional. Informe TRAMIL. Laboratorio de fitofarmacología, Dep. de Farmacología, Facultad de Salud, Universidad del Valle, Cali, Colombia.

20 GARCIA GM, COTO MT, GONZALEZ CS, PAZOS L, 2000
Toxicidad aguda en ratones, del extracto acuoso de hojas frescas de Persea americana. Informe TRAMIL. Laboratorio de Ensayos Biológicos LEBi, Escuela de Medicina, Universidad de Costa Rica, San Pedro, Costa Rica.

21 LOPEZ M, MARTINEZ MJ, MOREJON Z, BOUCOURT E, FUENTES V, MORON F. 2005
Irritabilidad dérmica primaria de hoja fresca machacada de Persea americana Mill. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Medicina “Dr. Salvador Allende”, La Habana, Cuba.

22 CRAIGMILL AL, SEAWRIGHT AA, MATTILA T, FROST AJ, 1989
Pathological changes in the mammary gland and biochemical changes in milk of the goat following oral dosing with leaf of the avocado (Persea americana). Aust Vet J 66(7):206-211.

23 GRANT R, BASSON PA, BOOKER HH, HOFHERR JB, ANTHONISSEN M, 1991
Cardiomyopathy caused by avocado (Persea americana Mill.) leaves. J S Afr Vet Assoc 62(1):21-22.

(In territories with significant traditional TRAMIL use)

Haiti:

  • boul di mas

Dominican Republic:

  • magueyito
Significant uses found by the TRAMIL surveys

  hoja, decocción, vía oral2

Recommendations Preparation and Dosage References

According to published and other information:

Uses for late period (amenorrhea) without pregnancy, twisting and traumatism are classified as REC, based on the significant traditional use documented in the TRAMIL surveys, and on available published scientific information.

Topical use for headache is classified as REC, based on the significant traditional use (OMS/WHO)4 documented in the TRAMIL surveys.

Not for use by pregnant women for risk of abortion, during lactation or by children under 5 years old.

For late period (amenorrhea) other than pregnancy, apply treatment for three consecutive days.

Do not use decoction by oral administrationfor more than five consecutive days.

If the patient’s condition deteriorates, or if headache, twisting or traumatism persist for more than three days, seek medical attention.

Contact of the leaf with the skin may cause irritation5.

For headache, late period (amenorrhea), twisting or traumatism:

There is no available information establishing a means of preparation and dosage other than that referred to by traditional use.

Any medicinal preparation must be preserved cold and used within the 24 hours.

1 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

2 WENIGER B, ROUZIER M, 1986
Enquête TRAMIL. Service Oecuménique d'Entraide SOE, Port au Prince, Haïti.

3 WENIGER B, 1987-88
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.

4 WHO, 1991
Pautas para la evaluación de medicamentos herbarios WHO/TRM/91.4 (original inglés). Programa de Medicina Tradicional, OMS, Ginebra, Suiza.

5 LAMPE KF, FAGERSTRÖM R, 1968
Plant toxicity and dermatitis: A manual for physicians. Baltimore, USA: Williams & Wilkins.

6 IDAKA E, OGAWA T, KONDO T, GOTO T, 1987
Isolation of highly acylated anthocyanins from Commelinaceae plants, Zebrina pendula, Rhoeo spathacea and Setcreasea purpurea. Agr Biol Chem 51(8):2215-2220.

7 YEOH HH, WEE YC, WATSON L, 1986
Taxonomic variation in total leaf protein amino acid compositions of monocotyledonous plants. Biochem Syst Ecol 14(1):91-96.

8 WENIGER B, HAAG-BERRURIER M, ANTON R, 1982
Plants of Haiti used as antifertility agents. J of Ethnopharmacology 6(1):67-84.

9 GUPTA M, ESPOSITO AVELLA M, 1988
Evaluación química y farmacológica de algunas plantas medicinales de TRAMIL. Centro de Investigaciones Farmacognósticas de la Flora Panameña CIFLORPAN, Facultad de Farmacia, Universidad de Panamá, Panamá, Panamá. TRAMIL III, La Habana, Cuba, MINSAP/enda-caribe.

10 PEREZ RM, 1996
Anti-inflammatory activity of Ambrosia artemisiaefolia and Rhoeo spathacea. Phytomedicine 3(2):163-167.

11 SUFFNESS M, ABBOTT B, STATZ DW, WONILOWICZ E, SPJUT R, 1988
The utility of P388 leukemia compared to B16 melanoma and colon carcinoma 38 for in vivo screening of plant extracts. Phytother Res 2(2):89-97.