abnormal vaginal discharge

Solanum americanum

(In territories with significant traditional TRAMIL use)

Guatemala:

  • hierbamora
  • macuy
  • quilete

Venezuela:

  • yerba mora
Significant uses found by the TRAMIL surveys

  ripe leaf, cut at the end of or after fruition, decoction, applied in vaginal washes1

Recommendations Preparation and Dosage References

According to published and other information:

Use for abnormal vaginal discharge and for culebrilla (herpes zoster) is classified as REC, based on the significant traditional use documented in the TRAMIL surveys and available published scientific information.

For topical application, strict hygiene measures should be observed in order to avoid contamination or additional infection.

Should there be a notable worsening of the patient’s condition, or should abnormal vaginal discharge persist for more than 7 days, seek medical attention.

The young fresh plant and the ripe fruit are widely used for human consumption12-14.

For culebrilla (herpes zoster):

Wash injury with 30-50 grams (1 handful) of mashed leaf and fruit.  Apply in sufficient quantity to affected area 2 times a day15.

For abnormal vaginal discharge:

Prepare a decoction with 30-50 grams (1 handful) of leaf in 1 liter (4 cups) of water. Boil for at least 10 minutes in a covered pot, filter, allow to cool down and use for sitz baths and vaginal washes 3 times a day16.

Any medicinal preparation must be preserved cold and used within the 24 hours.

1 GIRON L, 1988
Encuesta TRAMIL (Costa atlántica). Centro Mesoamericano de Tecnología CEMAT, Guatemala, Guatemala.

2 DELENS M, 1990
Encuesta TRAMIL en Barlovento, Edo. Miranda de Venezuela. Centro al Servicio de la Acción Popular CESAP, Caracas, Venezuela.

3 GOMEZ H, 2003
Estudio fitoquímico de algunas plantas promisorias del Caribe colombiano. Informe TRAMIL. Grupo de Productos Naturales, Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Cartagena, Cartagena de Indias, Colombia.

4 MOREJON Z, VICTORIA MC, MORON F, MENDEZ G, FUENTES V, 2006
Tamizaje fitoquímico de la un extracto fluido de partes aéreas secas de Solanum americanum . Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Ciencias Médicas “Dr. Salvador Allende”, La Habana, Cuba.

5 ALDANA MV, LIMA CN, 1999
Isolation and characterization of a glycoside from fluid extracts of Solanum americanum Mill. Afinidad 56(484):393-396.

6 CACERES A, ALVAREZ AV, OVANDO AE, SAMAYOA B, 1991
Plants used in Guatemala for the treatment of respiratory diseases. 1. Screening of 68 plants against Gram-positive bacteria. J Ethnopharmacol 31(2):193-208.

7 VICTORIA AE, 1980
Investigación farmacológica de la acción hipoglucemiante de la hoja de Solanum nigrescens Mart & Gal. (macuy, quilete o hierba mora). Tesis Guatemala, Facultad de CCUU y Farmacia, USAC, Guatemala, Guatemala.

8 COONEY G, BUCKLEY H, BRICKUS T, CACERES A, 1991
Fungicidal activity of Solanum plant extract from Guatemala, C.A. Abstracts CD52. Pharmacy Word Cong, Washington DC, USA.

9 CACERES A, LOPEZ BR, GIRON MA, LOGEMANN H, 1991
Plants used in Guatemala for the treatment of dermatophytic infections. 1. Screening for antimycotic activity of 44 plant extracts. J Ethnopharmacol 31(3):263-276.

10 SANCHEZ LM, BULNES C, PEREZ P, RODRIGUEZ A, NOA M, GINORIO C, GOMEZ BC, 2003
Actividad antibacteriana, cicatrizante y útero-estimulante de Solanum americanum Miller. Actualidades Biológicas 25(78):71-78.

11 LOPEZ M, MARTINEZ MJ, MOREJON Z, BOUCOURT E, FERRADA C, FUENTES V, MORON F, 2005
Irritabilidad dérmica primaria de una decocción de hoja seca Solanum americanum Mill. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Medicina “Dr. Salvador Allende”, La Habana, Cuba.

12 PAZOS L, COTO T, CAIZA F, 2009                                                                                                                                                                                                                                                                     Irritación dérmica, piel sana en conejos, porción de hoja fresca de Solanum americanum. Informe TRAMIL. Laboratorio de Ensayos Biológicos, LEBi, Universidad de Costa Rica, San Pedro, Costa Rica.

13 MARTINEZ MJ, LOPEZ M, MOREJON Z, BOUCOURT E, FUENTES V, MORON F, 2005
Irritabilidad vaginal de decocción de hoja seca de Solanum americanum. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Ciencias Médicas “Dr. Salvador Allende”, La Habana, Cuba.

14 MARTINEZ MJ, LOPEZ M, MOREJON Z, BOUCOURT E, FUENTES V, MORON F, 2005
Clases tóxicas agudas oral de decocción de hoja seca, de tallo seco y de frutos verdes secos de Solanum americanum. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Ciencias Médicas "Dr. Salvador Allende", La Habana, Cuba.

15 ALTSCHUL S, 1973
Drugs and food from little-known plants: Notes in Harvard University Herbaria. Cambridge, USA: Harvard Univ Press.

16 MORTON J, 1977
Some folk-remedy plants of Central American markets. Quart J Crude Drug Res 15:165-192.

17 SOUZA-NOVELO N, 1950
Plantas alimenticias y plantas de condimento que viven en Yucatán. Mérida, México: Inst.Tecn.Agrícola Henequenero.

18 ALBORNOZ A, 1993
Medicina Tradicional Herbaria. Caracas Venezuela: Editorial Instituto Farmacoterápico Latino S.A. p132.

19 CACERES A, 1996
Plantas de uso medicinal en Guatemala. Ciudad de Guatemala, Guatemala: Editorial Universitaria. p315.

 

Solanum nigrescens

(In territories with significant traditional TRAMIL use)

Guatemala:

  • hierba mora
  • macuy
  • quilete
Significant uses found by the TRAMIL surveys

  ripe leaf, cut at the end of or after fruition, decoction, applied locally, vaginal wash1

Recommendations Preparation and Dosage References

According to published and other information:

Use for abnormal vaginal discharge is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, toxicity studies, scientific validation and available published scientific information.

For topical application, strict hygiene measures should be observed in order to avoid contamination or additional infection.

Should there be a notable worsening of the patient’s condition, or should the symptoms persist for more than 7 days, seek medical attention.

For abnormal vaginal discharge:

Prepare a decoction with 30 grams (10 spoonfuls) of ripe leaf in 1 liter (4 cups) of water. Boil for at least 10 minutes in a covered pot, allow to cool down and apply as sitz baths and vaginal washes11, 3 times a day1, during 15 days5.

Any medicinal preparation must be preserved cold and used within the 24 hours.

1 GIRON L, 1988
Encuesta TRAMIL (Costa atlántica). Centro Mesoamericano de Tecnología CEMAT, Guatemala, Guatemala.

2 HE XG, MOCEK U, FLOSS HG, CACERES A, GIRON L, BUCKLEY H, COONEY G, MANNS J, WILSON BW, 1994
An antifungal compound from Solanum nigrescens. J Etnopharmacol 43(3):173-177.

3 GIRON L, 1983
Investigación de la inhibición de Candida albicans por preparaciones de plantas usadas en la medicina popular (Tesis Mag. Sc). Fac Ciencias Químicas y Farmacéuticas, Universidad de San Carlos de Guatemala USAC, Guatemala, Guatemala.

4 CACERES A, GIRON L, ALVARADO S, TORRES M, 1987
Screening of antimicrobial activity of plants popularly used in Guatemala for the treatment of dermatomucosal diseases. J Ethnopharmacol 20(3):223-237.

5 GIRON LM, AGUILAR GA, CACERES A, ARROYO GL, 1988
Anticandidal activity of plants used for the treatment of vaginitis in Guatemala and clinical trial of a Solanum nigrescens preparation. J Etnopharmacol 22(3):307-313.

6 CACERES A, LOPEZ BR, GIRON MA, LOGEMANN H, 1991
Plants used in Guatemala for the treatment of dermatophytic infections. 1. Screening for antimycotic activity of 44 plant extracts. J Ethnopharmacol 31(3):263-276.

7 COONEY G., BUCKLEY H, BRICKUS T, CACERES A, 1991
Fungicidal activity of a Solanum plant extract from Guatemala, CA. Pharmacy World Congress, Washington, USA. CS 52.

8 LARA R, SANDOVAL H, JIMENEZ M, DE LA ROCA D, GUZMAN A, 1991
Determinación de la actividad inmunomoduladora de los extractos de zarzaparrilla, quilete y pericón. IV Congreso Nacional de Microbiología, Guatemala, Guatemala.

9 AGUILAR G, 1985
Tratamiento de la candidosis vaginal con extracto de Solanum nigrescens (Tesis Mag. Sc). Fac Ciencias Químicas y Farmacéuticas, Universidad de San Carlos de Guatemala USAC, Guatemala, Guatemala.

10 GIRON L, 1992
Toxicidad aguda del extracto acuoso de Solanum nigrescens. Informe TRAMIL. FARMAYA, Guatemala, Guatemala.

11 GIRON L, CACERES A, FREIRE V, ALONZO A, SALVADOR L, 1995
Folleto informativo sobre algunas plantas comúnmente utilizadas por la población Garifuna de Livingston, Guatemala, Guatemala, p45.