(In territories with significant traditional TRAMIL use)
Haiti:
- bwa kanpèch
(In territories with significant traditional TRAMIL use)
(In territories with significant traditional TRAMIL use)
leaf mashed, applied locally7
According to published and other information: Use for constipation is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, toxicity studies, scientific validation and available published scientific information. Uses for ganglionar disorder, headache, toothache, earache, pneumonia, asthma, burns, rheumatism, twisting and trauma are classified as REC, based on the significant traditional use (OMS/WHO)4 documented in the TRAMIL surveys, and, when the leaf is topically applied, based on toxicity studies. When the seed oil is taken orally, a single dose should be used. For topical application to burns, strict hygiene measures should be observed in order to avoid contamination or additional infection. Limit traditional use only to superficial burns (skin injuries) that are not extensive (covering less than 10% of body surface) and are located away from high risk areas such as face, hands, feet and genitals. Due to the health risks involved with pneumonia, asthma, earache and ganglionar disorder, an initial medical evaluation is recommended. The use of this resource can be considered complementary to medical treatment, unless it is contraindicated. Due to the possibility that an earache could signal a middle or inner ear infection, immediate medical evaluation is recommended. Do not use if there are secretions from the ear and/or possible perforation of the eardrum. The seed can cause reactions of hypersensitivity. Should there be a notable worsening of the patient’s condition, the asthma persisting for more than 2 days, the headache and the twisting lasting more than 3 days or the pneumonia 5 days, seek medical attention. Only the oil that has been hand-made following traditional procedures, or the oil purchased in a pharmacy or authorized center should be used. Industrially-produced ricin oil has not been subject to albumin detoxification through vaporization, and is a highly toxic product whose ingestion may lead to an imminently life-threatening situation.
For constipation: Take the seed oil - purchased in a pharmacy or authorized health center- at doses of: 1-3 spoonfuls (15-45 mL) for adults, 1-3 teaspoonfuls (5-15 mL) for children older than 2 years, and 1-5 mL for children younger than 2 years. Take orally in a single dose away from meals. Can be taken with milk, tea or fruit juice28. For other uses: There is no available information establishing a means of preparation and dosage other than the documented traditional uses. Any medicinal preparation must be preserved cold and used within the 24 hours.
1 WENIGER B, ROUZIER M, 1986
Enquête TRAMIL. Service Oecuménique d'Entraide SOE, Port au Prince, Haïti.
2 JEAN-PIERRE L, 1988
TRAMIL survey. St Lucia national herbarium, Castries, St Lucia.
3 EDOUARD JA, 1992
Enquête TRAMIL. Lycée agricole, Baie-Mahault, Guadeloupe.
4 FAUJOUR A, MURREY D, CHELTENHAM-CORBIN B, CARRINGTON S, 2003
TRAMIL survey. enda-caribbean, IICA & UAG, Saint Thomas, Barbados.
5 BALZ E, BOYER A, BURAUD M, 2007
Enquête TRAMIL à Marie-Galante. U. Bordeaux 3, U. Paris XI Chatenay-Malabry, UAG, Guadeloupe.
6 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.
7 CHARLES C, 1988
TRAMIL survey. Movement for Cultural Awareness MCA, Roseau, Dominica.
8 BOULOGNE I, 2008
Enquête TRAMIL à Terre-de-Haut, Les Saintes, UAG, Guadeloupe (FWI).
9 WENIGER B, 1987-88
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.
10 BOYER A, BURAUD M, 2007
Enquête TRAMIL à La Désirade. U. Paris XI Chatenay-Malabry, UAG, Guadeloupe.
11 LONGUEFOSSE JL, NOSSIN E, 1990-95
Enquête TRAMIL. Association pour la valorisation des plantes médicinales de la Caraïbe AVPMC, Fort de France, Martinique.
12 HEGNAUER R, 1973
Chemotaxonomy der Pflanzen. Basel, Schweiz: Birkhauser Verlag.
13 CHONKEL A, 1985
A propos de quelques graines toxiques existant à la Guadeloupe. Thèse Pharmacie, Montpellier, France.
14 DUKE JA, 1992
Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, USA: CRC Press.
15 DUKE JA, ATCHLEY AA, 1986
Handbook of proximate analysis tables of higher plants. Boca Raton, USA: CRC Press. p140.
16 DE SOUSA M, Matos ME, Matos FJ, MACHADO MI, CRAVEIRO AA, 1991
Constituintes químicos ativos de plantas medicinais Brasileiras. Laboratorio de produtos naturais, Fortaleza, Brasil: Ceará Edições UFC.
17 TSUPRIENKOVA T, 1982
Patente de autor de champú para el lavado del cabello (título original en ruso). URSS, A61K 7/06(53).
18 WENIGER B, 1992
Activités biologiques (cytotoxicité, effet sur la croissance, effet immunomodulateur) de drogues végétales de la Caraïbe utilisées par voie locale contre les brûlures, dans des systèmes de cellules animales et humaines en culture. Faculté de Pharmacie, Université de Strasbourg, Illkirch, France.
19 FRIAS AI, CABRERA H, GARCIA N, MORON F, VICTORIA MC, GERMOSEN-ROBINEAU, 2011
Efecto antiinflamatorio tópico del aceite de semilla de Ricinus communis (aceite de ricino) en el edema de la oreja inducido por aceite de Croton en ratones. Trabajo TRAMIL. Laboratorio Central de Farmacología. Universidad de Ciencias Médicas de La Habana, Cuba.
20 VERPOORTE R, DIHAL PP, 1987
Medicinal plants of Surinam IV. Antimicrobial activity of some medicinal plants. J Etnopharmacol 21(3):315-318.
21 MISAS CA, HERNANDEZ NM, ABRAHAM AM, 1979
Contribution to the biological evaluation of Cuban plants. I. Rev Cub Med Trop 31:5-12.
22 TANIRA MO, AGEEL AM, AL-SAID MS, 1989
A study on some Saudi medicinal plants used as diuretics in traditional medicine. Fitoterapia 60(5):443-447.
23 CECIL, RUSELL LA FAYETTE, 1987
Compendio de Medicina Interna. Madrid, España: Ed. Interamericana.
24 MARTINEZ MJ, LOPEZ M, MOREJON Z, BOUCOURT E, FUENTES V, MORON F, 2005
Irritabilidad dérmica primaria de semillas frescas peladas y machacadas de Ricinus communis L. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Ciencias Médicas “Dr. Salvador Allende”, La Habana, Cuba.
25 MARTINEZ MJ, MOREJON Z, BOUCOURT E, FUENTES V, MORON F, 2003
Irritabilidad dérmica primaria de hoja seca y de hoja fresca de Ricinus communis L. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Medicina “Dr. Salvador Allende”, La Habana, Cuba.
26 ROCHA E SILVA M, 1943
Studies on poisonous plants in the state of Sao Paulo. Toxicological expts on 27 plants which have been suspected of toxicity. Arq Inst Biol (Sao Paulo) 14:15.
27 CANELLA CFC, TOKARNIA CH, DOBEREINER J, 1966
Experiments with plants supposedly toxic to cattle in Northeastern Brazil, with negative results. Pesqui Agropecu Brasil Ser Vet 1:345-352.
28 KHOLKUTE SD, MUDGAL V, DESHPANDE PJ, 1976
Screening of indigenous medicinal plants for antifertility potentiality. Planta Med 29(2):150-155.
29 KANERVA L, ESTLANDER T, JOLANKI R, 1990
Long-lasting contact urticaria from castor bean. J Amer Acad Dermatol 23(2):351-355.
30 GOWANLOCH JN, BROWN CA, 1943
Poisonous snakes, plants and black widow spider of Louisiana, Dept. Conservation, New Orleans,Louisiana. Book.
31 OZTEKIN-MAT A, 1994
Plant poisoning in Turkey. Ann Pharm Fr 52(5):260-265.
32 KOPFERSCHMITT J, FLESCH F, LUGNIER A, SAUDER P, JAEGER A, MANTZ JM, 1983
Acute voluntary intoxication by ricin. Human Toxicol 2(2):239-242.
33 CANIGUERAL S, 2003
Ricinus comunis. Vademecum de Fitoterapia, Editorial Masson, Barcelona, España, Jul.30,2003. URL: www.masson.es/book/fitoterapia.html
34 IRWIN R, 1992
Toxicity studies of castor oil in F344/N rats and B6C3F1 mice (dosed feed studies). Natl Toxicol Program Tech Rep SER 1992:25.
35 WEE YC, GOPALAKRISHNAKONE P, CHAN A, 1988
Poisonous plants in Singapore - a colour chart for identification with symptoms and signs of poisoning. Toxicon 26(1):47.
36 ALONSO J, 1998
Tratado de fitomedicina. Bases clínicas y farmacológicas. Buenos Aires, Argentina: ISIS ediciones SRL. p840.
37 FERNANDO R, 1988
Plant poisoning in Sri Lanka. Toxicon 26(1):20.
38 PERIS JB, STUBING G, 2003
Ricinus comunis. Vademecum de Fitoterapia, Editorial Masson, Barcelona, España, Jul.30,2003. URL: www.masson.es/book/fitoterapia.html
(In territories with significant traditional TRAMIL use)
seed oil, applied locally5
According to published and other information: Use for constipation is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, toxicity studies, scientific validation and available published scientific information. Uses for ganglionar disorder, headache, toothache, earache, pneumonia, asthma, burns, rheumatism, twisting and trauma are classified as REC, based on the significant traditional use (OMS/WHO)4 documented in the TRAMIL surveys, and, when the leaf is topically applied, based on toxicity studies. When the seed oil is taken orally, a single dose should be used. For topical application to burns, strict hygiene measures should be observed in order to avoid contamination or additional infection. Limit traditional use only to superficial burns (skin injuries) that are not extensive (covering less than 10% of body surface) and are located away from high risk areas such as face, hands, feet and genitals. Due to the health risks involved with pneumonia, asthma, earache and ganglionar disorder, an initial medical evaluation is recommended. The use of this resource can be considered complementary to medical treatment, unless it is contraindicated. Due to the possibility that an earache could signal a middle or inner ear infection, immediate medical evaluation is recommended. Do not use if there are secretions from the ear and/or possible perforation of the eardrum. The seed can cause reactions of hypersensitivity. Should there be a notable worsening of the patient’s condition, the asthma persisting for more than 2 days, the headache and the twisting lasting more than 3 days or the pneumonia 5 days, seek medical attention. Only the oil that has been hand-made following traditional procedures, or the oil purchased in a pharmacy or authorized center should be used. Industrially-produced ricin oil has not been subject to albumin detoxification through vaporization, and is a highly toxic product whose ingestion may lead to an imminently life-threatening situation.
For constipation: Take the seed oil - purchased in a pharmacy or authorized health center- at doses of: 1-3 spoonfuls (15-45 mL) for adults, 1-3 teaspoonfuls (5-15 mL) for children older than 2 years, and 1-5 mL for children younger than 2 years. Take orally in a single dose away from meals. Can be taken with milk, tea or fruit juice28. For other uses: There is no available information establishing a means of preparation and dosage other than the documented traditional uses. Any medicinal preparation must be preserved cold and used within the 24 hours.
1 WENIGER B, ROUZIER M, 1986
Enquête TRAMIL. Service Oecuménique d'Entraide SOE, Port au Prince, Haïti.
2 JEAN-PIERRE L, 1988
TRAMIL survey. St Lucia national herbarium, Castries, St Lucia.
3 EDOUARD JA, 1992
Enquête TRAMIL. Lycée agricole, Baie-Mahault, Guadeloupe.
4 FAUJOUR A, MURREY D, CHELTENHAM-CORBIN B, CARRINGTON S, 2003
TRAMIL survey. enda-caribbean, IICA & UAG, Saint Thomas, Barbados.
5 BALZ E, BOYER A, BURAUD M, 2007
Enquête TRAMIL à Marie-Galante. U. Bordeaux 3, U. Paris XI Chatenay-Malabry, UAG, Guadeloupe.
6 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.
7 CHARLES C, 1988
TRAMIL survey. Movement for Cultural Awareness MCA, Roseau, Dominica.
8 BOULOGNE I, 2008
Enquête TRAMIL à Terre-de-Haut, Les Saintes, UAG, Guadeloupe (FWI).
9 WENIGER B, 1987-88
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.
10 BOYER A, BURAUD M, 2007
Enquête TRAMIL à La Désirade. U. Paris XI Chatenay-Malabry, UAG, Guadeloupe.
11 LONGUEFOSSE JL, NOSSIN E, 1990-95
Enquête TRAMIL. Association pour la valorisation des plantes médicinales de la Caraïbe AVPMC, Fort de France, Martinique.
12 HEGNAUER R, 1973
Chemotaxonomy der Pflanzen. Basel, Schweiz: Birkhauser Verlag.
13 CHONKEL A, 1985
A propos de quelques graines toxiques existant à la Guadeloupe. Thèse Pharmacie, Montpellier, France.
14 DUKE JA, 1992
Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, USA: CRC Press.
15 DUKE JA, ATCHLEY AA, 1986
Handbook of proximate analysis tables of higher plants. Boca Raton, USA: CRC Press. p140.
16 DE SOUSA M, Matos ME, Matos FJ, MACHADO MI, CRAVEIRO AA, 1991
Constituintes químicos ativos de plantas medicinais Brasileiras. Laboratorio de produtos naturais, Fortaleza, Brasil: Ceará Edições UFC.
17 TSUPRIENKOVA T, 1982
Patente de autor de champú para el lavado del cabello (título original en ruso). URSS, A61K 7/06(53).
18 WENIGER B, 1992
Activités biologiques (cytotoxicité, effet sur la croissance, effet immunomodulateur) de drogues végétales de la Caraïbe utilisées par voie locale contre les brûlures, dans des systèmes de cellules animales et humaines en culture. Faculté de Pharmacie, Université de Strasbourg, Illkirch, France.
19 FRIAS AI, CABRERA H, GARCIA N, MORON F, VICTORIA MC, GERMOSEN-ROBINEAU, 2011
Efecto antiinflamatorio tópico del aceite de semilla de Ricinus communis (aceite de ricino) en el edema de la oreja inducido por aceite de Croton en ratones. Trabajo TRAMIL. Laboratorio Central de Farmacología. Universidad de Ciencias Médicas de La Habana, Cuba.
20 VERPOORTE R, DIHAL PP, 1987
Medicinal plants of Surinam IV. Antimicrobial activity of some medicinal plants. J Etnopharmacol 21(3):315-318.
21 MISAS CA, HERNANDEZ NM, ABRAHAM AM, 1979
Contribution to the biological evaluation of Cuban plants. I. Rev Cub Med Trop 31:5-12.
22 TANIRA MO, AGEEL AM, AL-SAID MS, 1989
A study on some Saudi medicinal plants used as diuretics in traditional medicine. Fitoterapia 60(5):443-447.
23 CECIL, RUSELL LA FAYETTE, 1987
Compendio de Medicina Interna. Madrid, España: Ed. Interamericana.
24 MARTINEZ MJ, LOPEZ M, MOREJON Z, BOUCOURT E, FUENTES V, MORON F, 2005
Irritabilidad dérmica primaria de semillas frescas peladas y machacadas de Ricinus communis L. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Ciencias Médicas “Dr. Salvador Allende”, La Habana, Cuba.
25 MARTINEZ MJ, MOREJON Z, BOUCOURT E, FUENTES V, MORON F, 2003
Irritabilidad dérmica primaria de hoja seca y de hoja fresca de Ricinus communis L. Informe TRAMIL. Laboratorio Central de Farmacología, Facultad de Medicina “Dr. Salvador Allende”, La Habana, Cuba.
26 ROCHA E SILVA M, 1943
Studies on poisonous plants in the state of Sao Paulo. Toxicological expts on 27 plants which have been suspected of toxicity. Arq Inst Biol (Sao Paulo) 14:15.
27 CANELLA CFC, TOKARNIA CH, DOBEREINER J, 1966
Experiments with plants supposedly toxic to cattle in Northeastern Brazil, with negative results. Pesqui Agropecu Brasil Ser Vet 1:345-352.
28 KHOLKUTE SD, MUDGAL V, DESHPANDE PJ, 1976
Screening of indigenous medicinal plants for antifertility potentiality. Planta Med 29(2):150-155.
29 KANERVA L, ESTLANDER T, JOLANKI R, 1990
Long-lasting contact urticaria from castor bean. J Amer Acad Dermatol 23(2):351-355.
30 GOWANLOCH JN, BROWN CA, 1943
Poisonous snakes, plants and black widow spider of Louisiana, Dept. Conservation, New Orleans,Louisiana. Book.
31 OZTEKIN-MAT A, 1994
Plant poisoning in Turkey. Ann Pharm Fr 52(5):260-265.
32 KOPFERSCHMITT J, FLESCH F, LUGNIER A, SAUDER P, JAEGER A, MANTZ JM, 1983
Acute voluntary intoxication by ricin. Human Toxicol 2(2):239-242.
33 CANIGUERAL S, 2003
Ricinus comunis. Vademecum de Fitoterapia, Editorial Masson, Barcelona, España, Jul.30,2003. URL: www.masson.es/book/fitoterapia.html
34 IRWIN R, 1992
Toxicity studies of castor oil in F344/N rats and B6C3F1 mice (dosed feed studies). Natl Toxicol Program Tech Rep SER 1992:25.
35 WEE YC, GOPALAKRISHNAKONE P, CHAN A, 1988
Poisonous plants in Singapore - a colour chart for identification with symptoms and signs of poisoning. Toxicon 26(1):47.
36 ALONSO J, 1998
Tratado de fitomedicina. Bases clínicas y farmacológicas. Buenos Aires, Argentina: ISIS ediciones SRL. p840.
37 FERNANDO R, 1988
Plant poisoning in Sri Lanka. Toxicon 26(1):20.
38 PERIS JB, STUBING G, 2003
Ricinus comunis. Vademecum de Fitoterapia, Editorial Masson, Barcelona, España, Jul.30,2003. URL: www.masson.es/book/fitoterapia.html
(In territories with significant traditional TRAMIL use)
hoja, decocción, vía oral2-3
According to published and other information:
Uses for late period (amenorrhea) without pregnancy, twisting and traumatism are classified as REC, based on the significant traditional use documented in the TRAMIL surveys, and on available published scientific information.
Topical use for headache is classified as REC, based on the significant traditional use (OMS/WHO)4 documented in the TRAMIL surveys.
Not for use by pregnant women for risk of abortion, during lactation or by children under 5 years old.
For late period (amenorrhea) other than pregnancy, apply treatment for three consecutive days.
Do not use decoction by oral administrationfor more than five consecutive days.
If the patient’s condition deteriorates, or if headache, twisting or traumatism persist for more than three days, seek medical attention.
Contact of the leaf with the skin may cause irritation5.
For headache, late period (amenorrhea), twisting or traumatism:
There is no available information establishing a means of preparation and dosage other than that referred to by traditional use.
Any medicinal preparation must be preserved cold and used within the 24 hours.
1 GERMOSEN-ROBINEAU L, GERONIMO M, AMPARO C, 1984
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.
2 WENIGER B, ROUZIER M, 1986
Enquête TRAMIL. Service Oecuménique d'Entraide SOE, Port au Prince, Haïti.
3 WENIGER B, 1987-88
Encuesta TRAMIL. enda-caribe, Santo Domingo, Rep. Dominicana.
4 WHO, 1991
Pautas para la evaluación de medicamentos herbarios WHO/TRM/91.4 (original inglés). Programa de Medicina Tradicional, OMS, Ginebra, Suiza.
5 LAMPE KF, FAGERSTRÖM R, 1968
Plant toxicity and dermatitis: A manual for physicians. Baltimore, USA: Williams & Wilkins.
6 IDAKA E, OGAWA T, KONDO T, GOTO T, 1987
Isolation of highly acylated anthocyanins from Commelinaceae plants, Zebrina pendula, Rhoeo spathacea and Setcreasea purpurea. Agr Biol Chem 51(8):2215-2220.
7 YEOH HH, WEE YC, WATSON L, 1986
Taxonomic variation in total leaf protein amino acid compositions of monocotyledonous plants. Biochem Syst Ecol 14(1):91-96.
8 WENIGER B, HAAG-BERRURIER M, ANTON R, 1982
Plants of Haiti used as antifertility agents. J of Ethnopharmacology 6(1):67-84.
9 GUPTA M, ESPOSITO AVELLA M, 1988
Evaluación química y farmacológica de algunas plantas medicinales de TRAMIL. Centro de Investigaciones Farmacognósticas de la Flora Panameña CIFLORPAN, Facultad de Farmacia, Universidad de Panamá, Panamá, Panamá. TRAMIL III, La Habana, Cuba, MINSAP/enda-caribe.
10 PEREZ RM, 1996
Anti-inflammatory activity of Ambrosia artemisiaefolia and Rhoeo spathacea. Phytomedicine 3(2):163-167.
11 SUFFNESS M, ABBOTT B, STATZ DW, WONILOWICZ E, SPJUT R, 1988
The utility of P388 leukemia compared to B16 melanoma and colon carcinoma 38 for in vivo screening of plant extracts. Phytother Res 2(2):89-97.